Use prefetch to download data from the SRA to

download_expression_data(runs, sra_dir, verbose = TRUE)

Arguments

runs:

data.frame with columns ['study_accession', 'run_accession']

sra_dir:

directory where to save the expression data

Details

<sra_dir>/<run_accesion>/<run_accession>.sra

Each expression run is ~8 Gb, so roughly 1000 runs will require approximately 8 terabytes of space