All functions

build_coexp_direct_network()

Build Direct Co-Expression network

build_coexp_intra_study_spearman_network()

Build Co-exp network for each study and average

date_code()

create date code of the form YYYYMMDD inputs: d (optional): date code in the format of Sys.Date() for which to generate the date code, defaulting to 'today'

download_expression_data()

Download RNA-Seq expression runs from SRA

estimate_expression()

Estimate expression data from SRA run and reference genome

gather_estimated_expression()

Gather estimated expression data for analysis

gather_estimated_expression_meta()

Gather estimated expression data metadata

get_deepfri_predictions()

Use the DeepFRI webserver to get sequence and structure based gene function prediction

get_sra_connection()

Get connection to the sequence read archive database

load_parameters()

Load parameters

network_gba()

Evaluate network Guilt By Association and report AUROC scores

plot_network_heatmap()

Plot network heatmap

prepare_reference_genome()

Use RSEM to prepare reference genome

propagate_go_annotations()

Propagate GO term annotations

read_biogrid_tab2()

parse BioGRID tab2 format

retrieve_sra_runs()

Retrieve SRA runs from the SRAmeta database

submit_estimate_expression_slurm()

Submit estimate gene expression job to SLURM cluster

validate_downloaded_runs()

Check that the downloaded runs are not corrupted

validate_estimated_expression()

Validate estimated expression runs